Hillsboro, Missouri is the county seat of Jefferson County, and is Missouri’s fifth largest county by population. The residents of Hillsboro and the surrounding areas enjoy the comfort and serenity of a rural setting that is located a short drive from Saint Louis and its vast array of cultural opportunities, professional sports, fine dining, and abundant shopping.

 The 63050 zip code includes the town of Hillsboro, as well as dozens of near by residential developments. Three upscale residential lake developments are within a few miles of our city limits. Hillsboro is a progressive community looking forward to future growth and change while preserving its rich historical heritage.